A Study on Plasma Levels of Testosterone and Dehydroepiandrosterone - sulfate ( DHEA - S ) in the Patients with Acne Vulgaris / 대한피부과학회지

This study was performed to detect the hormonal abnormalities and to investigate the relationship between the levels of plasma testosterone and DHEA-S in 21 female patients with acne vulgaris using radioimmunoassay. The results were as follows : 1. The levels of plasma testosterone in patients group and control group(n=9) were 352+/-11.8 ng/dl, 223+/-9.7 ng/dl, respectively, and significantly elevated in patient group(p < 0.01), 2. The levels of plasma DHEA-S in patient group and control group were 286.6+/-126.8 pg/dl, 238.6+/-60.0 pg/dl, respectively, and did not show statistical significance. 3. The levels of plasma testosterones in patient subgroups classified by modified Pillsbury method were as follows minor group 32.6+5.3 ng/dl, mild group 33.4+/-15,5 ng/dl, moderate group 39.6+/-12.6 ng/dl. The testosterone levels in all the subgroups increased significantly than those in control group(352-t11.8 ng/dl) (p<0.05, p<0.05 p < 0.01) 4. The levels of plasrna DHEA-S in patient subgroups were follows minor group 242.5+/-412 pg/dl, mild group 263.9+/-166.1 pg/dl, moderate group 353.4+/-1273 pg/dl. The DE3EA-S levels in moderate group increased significantly than those in cotrol (238,6+/-60,0 pg/dl) and minor group(p<0.05). 5. There was no correlation between the plasma testosterone levels and the plasma DHEA-S levels in the acne patients.

A Case of Pseudoxanthomatous Mastocytosis / 대한피부과학회지

We report a case of pseudoxanthomatous mastocytosis that is an uncommon variant of urticaria pigmentosa. A 3 month-old boy visited our hospital with yellowish cutaneous nodules At the age of 2 months, small yellowish macule developed on the posterior neek, and during the following months, lesions spread to trunk, upper extremities, face, and scalp, most of them became gradually to the nodules. Darier's sign could be elicited easily. A biopsy of one. of the nodules or the back showed a very dense oval or cuboidal cells infiltrate in the dermis. Special stain with toluiddine blue showed this to he composed of mast cells. Electron microscopic examination revealed crowded mast. cells which was showing numerous cytoplasmic granules and long, thin villi. The patient: was managed symptomaticvlly and recommended to avoid mechanical or chemical irritation to the lesions.

A Case of Erythema Elevatum Diutinum Developed on the Unusual Sites / 대한피부과학회지

We report a case of 77-year old male with erythema elevatum diutinum, associated with pancytopenia, which developed on the unusual sites. Erythematous or brownish nodules developed on the face, neck, trunk, upper extremities and tongue. Histopathological examination of skin and tongue lesions showed perivascular infiltration of neutrophils, lymphocytes and nuclear dusts, and deposition of fibrinoid material within and around the vessel walls. His skin lesions improved slightly with systemic corticosteroid therapy.

Two Cases of Pseudocyst of Auricle / 대한피부과학회지

We present two cases of pseudocyst of auricle which occured in 59-year-old man and 21-year-old man. Each showed bean sized non-inflammatory cystic swelling of upper part of right auricle with slight tenderness and the cystic content was serosanguinous fluid. Cystic wall was composed of fibrovascular tissue replacing degenerated cartilage without lining epithelium.